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A patient with a history of chronic obstructive pulmonary disease (COPD) experiences an acute exacerbation.
Sputum culture grows numerous Gram-negative coccobacilli that are oxidase-positive and grow on chocolate agar but not on sheep blood agar. The MOST likely organism is:
A. Legionella pneumophila
B. Haemophilus influenzae
C. Moraxella catarrhalis
D. Streptococcus pneumoniae
Answer: B
NEW QUESTION # 201
A research laboratory is investigating the mechanism of action of a novel antiviral drug against herpes simplex virus. The drug is found to inhibit the viral DNA polymerase. Which of the following commercially available antiviral agents has a similar mechanism of action?
A. Acyclovir
B. Amantadine
C. Interferon-alpha
D. Oseltamivir
Answer: A
NEW QUESTION # 202
A patient with a history of inflammatory bowel disease is diagnosed with primary sclerosing cholangitis and undergoes liver transplantation. Post-transplant, they develop a bloodstream infection with a Gram-negative bacterium that is identified as Fusobacterium nucleatum. This organism's role in the pathogenesis of colorectal cancer is primarily attributed to its ability to:
A. Form biofilms that physically obstruct the bile ducts.
B. Produce potent exotoxins that damage the intestinal epithelium.
C. Directly induce mutations in colonic epithelial cells.
D. Modulate the host immune response and promote a pro-inflammatory microenvironment.
Answer: D
NEW QUESTION # 203
A research team is investigating the development of a novel vaccine against influenza virus. They are focusing on conserved epitopes within the hemagglutinin (HA) and neuraminidase (NA) proteins to elicit broadly neutralizing antibodies. Which of the following approaches is MOST likely to achieve this goal?
A. Utilizing a recombinant viral vector to deliver conserved epitopes of HA and NA.
B. Designing a subunit vaccine that presents highly variable regions of HA and NA.
C. Administering high doses of inactivated influenza vaccine annually.
D. Developing a live-attenuated influenza vaccine containing multiple serotypes.
Answer: A
NEW QUESTION # 204
A patient with a prosthetic joint develops a chronic infection. Multiple synovial fluid cultures grow a Gram- positive coccus that forms a biofilm and is resistant to multiple antibiotics, including methicillin and gentamicin. The MOST likely organism is:
A. Staphylococcus aureus
B. Streptococcus agalactiae
C. Enterococcus faecium
D. Staphylococcus epidermidis
Answer: D
NEW QUESTION # 205
......
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