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A clinical laboratory performs a cefoxitin disk diffusion test on a Staphylococcus aureus isolate from a wound culture. The zone of inhibition measures 18 mm. According to current CLSI M100 guidelines, how should this result be interpreted regarding oxacillin/methicillin susceptibility?
A. Resistant (report oxacillin as resistant; infer MRSA)
B. Indeterminate (requires mecA gene testing)
C. Susceptible (report oxacillin as susceptible)
D. Intermediate (requires MIC testing)
Answer: A
NEW QUESTION # 118
A patient with HIV infection and a CD4+ T-cell count below 50 cells/µL develops a progressive neurological illness characterized by confusion, motor deficits, and seizures. Brain MRI reveals multiple white matter lesions without mass effect. PCR of the CSF is positive for JC virus. Thepathogenesis of this condition, progressive multifocal leukoencephalopathy (PML), involves:
A. Direct cytopathic effect of JC virus on neurons.
B. Opportunistic infection by JC virus due to impaired cell-mediated immunity.
C. Inflammatory demyelination triggered by JC virus infection of astrocytes.
D. Lytic infection of oligodendrocytes by JC virus, leading to demyelination.
Answer: D
NEW QUESTION # 119
A patient presents with a pruritic rash consisting of raised, serpiginous tracks on their skin. The patient recently returned from a Caribbean vacation and reported walking barefoot on the beach. The MOST likely causative organism is:
A. Larvae of Ancylostoma braziliense
B. Larvae of Strongyloides stercoralis
C. Pediculus humanus
D. Sarcoptes scabiei
Answer: A
NEW QUESTION # 120
A patient develops a localized skin infection after being bitten by a tick. The infection is characterized by a slowly expanding erythematous rash with central clearing (erythema migrans). The MOST likely causative agent is:
A. Anaplasma phagocytophilum
B. Ehrlichia chaffeensis
C. Rickettsia rickettsii
D. Borrelia burgdorferi
Answer: D
NEW QUESTION # 121
A patient develops a febrile illness with jaundice and dark urine after receiving a blood transfusion.
Laboratory testing reveals an elevated level of unconjugated bilirubin and a positive direct Coombs test.
Serological testing is positive for antibodies against a protozoan parasite that infects erythrocytes. The MOST likely causative agent is:
A. Plasmodium falciparum
B. Babesia microti
C. Toxoplasma gondii
D. Trypanosoma cruzi
Answer: B
NEW QUESTION # 122
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