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CBIC CIC Valid Exam Bootcamp, Detail CIC Explanation
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CBIC Certified Infection Control Exam Sample Questions (Q17-Q22):NEW QUESTION # 17
During the past week, three out of four blood cultures from a febrile neonate in an intensive care unit grew coagulase-negative staphylococci. This MOST likely indicates:
- A. Infection.
- B. Contamination.
- C. Colonization.
- D. Laboratory error.
Answer: B
Explanation:
The scenario involves a febrile neonate in an intensive care unit (ICU) with three out of four blood cultures growing coagulase-negative staphylococci (CoNS) over the past week. The Certification Board of Infection Control and Epidemiology (CBIC) emphasizes accurate interpretation of microbiological data in the
"Identification of Infectious Disease Processes" domain, aligning with the Centers for Disease Control and Prevention (CDC) guidelines for healthcare-associated infections. Determining whether this represents a true infection, contamination, colonization, or laboratory error requires evaluating the clinical and microbiological context.
Option B, "Contamination," is the most likely indication. Coagulase-negative staphylococci, such as Staphylococcus epidermidis, are common skin flora and frequent contaminants in blood cultures, especially in neonates where skin preparation or sampling technique may be challenging. The CDC's "Guidelines for the Prevention of Intravascular Catheter-Related Infections" (2017) and the Clinical and Laboratory Standards Institute (CLSI) note that multiple positive cultures (e.g., two or more) are typically required to confirm true bacteremia, particularly with CoNS, unless accompanied by clear clinical signs of infection (e.g., worsening fever, hemodynamic instability) and no other explanation. The inconsistency (three out of four cultures) and the neonate's ICU setting-where contamination from skin or catheter hubs is common-suggest that the positive cultures likely result from contamination during blood draw rather than true infection. Studies, such as those in the Journal of Clinical Microbiology (e.g., Beekmann et al., 2005), indicate that CoNS in blood cultures is contaminated in 70-80% of cases when not supported by robust clinical correlation.
Option A, "Laboratory error," is possible but less likely as the primary explanation. Laboratory errors (e.g., mislabeling or processing mistakes) could occur, but the repeated growth in three of four cultures suggests a consistent finding rather than a random error, making contamination a more plausible cause. Option C,
"Colonization," refers to the presence of microorganisms on or in the body without invasion or immune response. While CoNS can colonize the skin or catheter sites, colonization does not typically result in positive blood cultures unless there is an invasive process, which is not supported by the data here. Option D,
"Infection," is the least likely without additional evidence. True CoNS bloodstream infections (e.g., catheter- related) in neonates are serious but require consistent positive cultures, clinical deterioration (e.g., persistent fever, leukocytosis), and often imaging or catheter removal confirmation. The febrile state alone, with inconsistent culture results, does not meet the CDC's criteria for diagnosing infection (e.g., at least two positive cultures from separate draws).
The CBIC Practice Analysis (2022) and CDC guidelines stress differentiating contamination from infection to avoid unnecessary treatment, which can drive antibiotic resistance. Given the high likelihood of contamination with CoNS in this context, Option B is the most accurate answer.
References:
* CBIC Practice Analysis, 2022.
* CDC Guidelines for the Prevention of Intravascular Catheter-Related Infections, 2017.
* Beekmann, S. E., et al. (2005). Coagulase-Negative Staphylococci in Blood Cultures. Journal of Clinical Microbiology.
* CLSI Guidelines on Blood Culture Interpretation, 2018.
NEW QUESTION # 18
What rate is expressed by the number of patients who acquire infections over a specified time period divided by the population at risk of acquiring an infection during that time period?
- A. Point prevalence
- B. Disease specific
- C. Incidence rate
- D. Period prevalence
Answer: C
Explanation:
The incidence rate measures new cases of infection in a population over a defined time period using the formula:

Why the Other Options Are Incorrect?
* B. Disease specific - Refers to infections caused by a particular pathogen, not the general rate of new infections.
* C. Point prevalence - Measures existing cases at a specific point in time, not new cases.
* D. Period prevalence - Includes both old and new cases over a set period, unlike incidence, which only considers new cases.
CBIC Infection Control Reference
APIC defines incidence rate as the number of new infections in a population over a given period.
NEW QUESTION # 19
In which of the following ways is human immunodeficiency virus similar to the Hepatitis B virus?
- A. The primary mechanism of transmission for both is maternal-fetal
- B. Needlestick exposure leads to a high frequency of healthcare worker infection
- C. The risk of infection from mucous membrane exposure is the same
- D. Transmission may occur from asymptomatic carriers
Answer: D
Explanation:
The human immunodeficiency virus (HIV) and Hepatitis B virus (HBV) are both bloodborne pathogens that pose significant risks in healthcare settings, and understanding their similarities is crucial for infection prevention and control. The Certification Board of Infection Control and Epidemiology (CBIC) emphasizes the importance of recognizing transmission modes and implementing appropriate precautions in the
"Prevention and Control of Infectious Diseases" domain, aligning with guidelines from the Centers for Disease Control and Prevention (CDC). Comparing these viruses involves evaluating their epidemiology, transmission routes, and occupational risks.
Option C, "Transmission may occur from asymptomatic carriers," is the correct answer. Both HIV and HBV can be transmitted by individuals who are infected but show no symptoms, making asymptomatic carriage a significant similarity. For HBV, chronic carriers (estimated at 257 million globally per WHO, 2019) can transmit the virus through blood, semen, or other bodily fluids without overt signs of disease. Similarly, HIV- infected individuals can remain asymptomatic for years during the latent phase, yet still transmit the virus through sexual contact, blood exposure, or perinatal transmission. The CDC's "Guidelines for Prevention of Transmission of HIV and HBV to Healthcare Workers" (1987, updated 2011) and "Epidemiology and Prevention of Viral Hepatitis" (2018) highlight this shared characteristic, underscoring the need for universal precautions regardless of symptom status.
Option A, "The primary mechanism of transmission for both is maternal-fetal," is incorrect. While maternal- fetal transmission (perinatal transmission) is a significant route for both HIV and HBV-occurring in 5-10% of cases without intervention for HBV and 15-45% for HIV without antiretroviral therapy-it is not the primary mechanism. For HBV, the primary mode is horizontal transmission through unprotected sexual contact or percutaneous exposure (e.g., needlesticks), accounting for the majority of cases. For HIV, sexual transmission and intravenous drug use are the leading modes globally, with maternal-fetal transmission being a smaller proportion despite its importance. Option B, "Needlestick exposure leads to a high frequency of healthcare worker infection," is partially true but not a precise similarity. Needlestick exposures carry a high risk for HBV (transmission risk ~30% if the source is HBeAg-positive) and a lower risk for HIV (~0.3%), but the frequency of infection among healthcare workers is significantly higher for HBV due to its greater infectivity and stability outside the host. This makes the statement more characteristic of HBV than a shared trait. Option D, "The risk of infection from mucous membrane exposure is the same," is false. The risk of HIV transmission via mucous membrane exposure (e.g., splash to eyes or mouth) is approximately 0.09%, while for HBV it is higher (up to 1-2% depending on viral load and exposure type), reflecting HBV's greater infectivity.
The CBIC Practice Analysis (2022) and CDC guidelines emphasize the role of asymptomatic transmission in shaping infection control strategies, such as routine testing and post-exposure prophylaxis. This shared feature of HIV and HBV justifies Option C as the most accurate similarity.
References:
* CBIC Practice Analysis, 2022.
* CDC Guidelines for Prevention of Transmission of HIV and HBV to Healthcare Workers, 2011.
* CDC Epidemiology and Prevention of Viral Hepatitis, 2018.
* WHO Hepatitis B Fact Sheet, 2019.
NEW QUESTION # 20
Using tap water to rinse suction tubing can cause transmission of
- A. Staphylococcus spp.
- B. Klebsiella spp.
- C. Streptococcus spp.
- D. Pseudomonas spp.
Answer: D
Explanation:
Pseudomonasspp., particularlyPseudomonas aeruginosa, is acommon waterborne pathogen. Using tap water to rinse suction tubing has been associated withoutbreaks ofPseudomonasinfections.
* From theAPIC Text:
"Water bottles improperly filled with tap water and used for rinsing tracheal suction tubing resulted in an outbreak ofP. cepacia... Tubing permanently attached to showers... implicated in a serious outbreak ofP.
aeruginosabloodstream infection."
References:
APIC Text, 4th Edition, Chapter 117 - Waterborne Pathogens
NEW QUESTION # 21
What is a characteristic of immediate-use steam sterilization?
- A. Substitute for maintaining sufficient amounts of sterile instruments.
- B. Can be used for the following surgery if properly stored.
- C. Performed in emergencies where cleaning is the most critical step.
- D. Alternative to purchasing expensive instrument sets.
Answer: A
Explanation:
The correct answer is C, "Substitute for maintaining sufficient amounts of sterile instruments," as this is a characteristic of immediate-use steam sterilization (IUSS). According to the Certification Board of Infection Control and Epidemiology (CBIC) guidelines, IUSS, formerly known as flash sterilization, is a process designed to rapidly sterilize items that are needed urgently when pre-sterilized inventory is unavailable or insufficient. It serves as a temporary solution to address gaps in sterile instrument availability, such as during unexpected surges in surgical demand or equipment shortages, provided strict protocols are followed (CBIC Practice Analysis, 2022, Domain III: Infection Prevention and Control, Competency 3.3 - Ensure safe reprocessing of medical equipment). However, IUSS is not a routine practice and should be minimized due to its limitations, including the lack of immediate biologic indicator results.
Option A (alternative to purchasing expensive instrument sets) is incorrect because IUSS is not intended as a cost-saving measure or a replacement for acquiring necessary equipment; it is a contingency process. Option B (can be used for the following surgery if properly stored) is misleading, as IUSS items are intended for immediate use and not for storage or use in subsequent procedures, which requires standard sterilization cycles with proper packaging and validation. Option D (performed in emergencies where cleaning is the most critical step) overemphasizes cleaning and mischaracterizes IUSS; while cleaning is a critical initial step, the process is defined by its rapid sterilization for emergency use, not solely by cleaning priority.
The characteristic of substituting for insufficient sterile instruments aligns with CBIC's focus on ensuring safe reprocessing practices while acknowledging the practical challenges in healthcare settings (CBIC Practice Analysis, 2022, Domain III: Infection Prevention and Control, Competency 3.5 - Evaluate the environment for infection risks). This is supported by AAMI ST79, which outlines IUSS as a last-resort measure to maintain surgical readiness (AAMI ST79:2017).
References: CBIC Practice Analysis, 2022, Domain III: Infection Prevention and Control, Competencies 3.3 - Ensure safe reprocessing of medical equipment, 3.5 - Evaluate the environment for infection risks. AAMI ST79:2017, Comprehensive guide to steam sterilization and sterility assurance in health care facilities.
NEW QUESTION # 22
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