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2026 American Society of Microbiology Realistic Brain Dump ABMM Free Pass Guaran
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American Society of Microbiology ABMM Sample Questions (Q114-Q119):NEW QUESTION # 114
Vancomycin resistance in Enterococcus faecium, mediated by the vanA gene cluster, results from:
- A. Decreased outer membrane permeability to vancomycin
- B. Modification of the drug target from D-alanyl-D-alanine to D-alanyl-D-lactate
- C. Efflux pump overexpression removing vancomycin from the cell
- D. Enzymatic inactivation of vancomycin by phosphorylation
Answer: B
NEW QUESTION # 115
A microbiology laboratory is performing antimicrobial susceptibility testing using the Kirby-Bauer disk diffusion method. A bacterial isolate shows no zone of inhibition around a specific antibiotic disk. This result could be due to:
- A. Intrinsic resistance of the organism to the antibiotic.
- B. The use of an incorrect inoculum density.
- C. All of the above.
- D. The antibiotic disk being stored improperly.
Answer: C
NEW QUESTION # 116
A clinical microbiology laboratory is investigating a potential outbreak of Legionella pneumophila associated with a hospital's water system. The MOST appropriate environmental samples to collect for culture and comparison to clinical isolates would be:
- A. Surface swabs from frequently touched objects.
- B. Water samples from showers, faucets, and cooling towers.
- C. Sputum samples from asymptomatic healthcare workers.
- D. Air samples from patient rooms and common areas.
Answer: B
NEW QUESTION # 117
A 55-year-old male with a history of poorly controlled diabetes mellitus develops a necrotizing fasciitis of his left lower extremity following a minor abrasion sustained while gardening. Initialcultures of the wound reveal a polymicrobial flora, including Gram-positive cocci in chains and Gram-negative bacilli. Over the next 48 hours, despite broad-spectrum antibiotic therapy, the patient's condition deteriorates, and new bullae with hemorrhagic fluid appear. Gram stain of this fluid now predominantly shows large, Gram-positive bacilli with subterminal spores. Which of the following virulence factors is MOST likely contributing to the rapid tissue destruction observed in this patient?
- A. Lecithinase (alpha-toxin)
- B. Lipopolysaccharide (LPS)
- C. Exotoxin B (SpeB)
- D. Protein A
Answer: A
NEW QUESTION # 118
A clinical microbiology laboratory is validating a new point-of-care test for the rapid detection of influenza A and B viruses. To accurately determine the clinical sensitivity of the test, it should be compared to a gold standard method using:
- A. Spiked samples containing known concentrations of influenza antigens.
- B. Samples from patients with other respiratory viral infections to assess cross-reactivity.
- C. A panel of known positive and negative samples stored at room temperature.
- D. A large number of prospectively collected clinical samples from patients with suspected influenza, with results confirmed by RT-PCR.
Answer: D
NEW QUESTION # 119
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