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American Society of Microbiology ABMM Sample Questions (Q55-Q60):NEW QUESTION # 55
During a primary infection with Epstein-Barr virus (EBV), the virus establishes latency in B lymphocytes.
The transition from lytic to latent infection is tightly regulated by viral gene expression. Which of the following viral proteins is crucial for the establishment and maintenance of EBV latency and is a key target in EBV-associated lymphomas?
- A. Early antigen (EA)
- B. Glycoprotein gp350
- C. Viral capsid antigen (VCA)
- D. Epstein-Barr nuclear antigen 1 (EBNA1)
Answer: D
NEW QUESTION # 56
A patient with a history of recurrent Clostridioides difficile infection (CDI) is being considered for fecal microbiota transplantation (FMT). Pre-FMT screening of the donor stool sample should include comprehensive testing to exclude potential transmission of enteric pathogens. Which of the following would be the MOST critical to rule out in the donor stool?
- A. Evidence of asymptomatic carriage of multidrug-resistant organisms (MDROs) such as vancomycin- resistant enterococci (VRE) or carbapenem-resistant Enterobacterales (CRE).
- B. Presence of non-toxigenic C. difficile strains.
- C. Detection of common antibiotic resistance genes not currently expressed.
- D. Quantification of the overall microbial diversity using 16S rRNA gene sequencing.
Answer: A
NEW QUESTION # 57
A laboratory worker sustains a needlestick injury while handling a blood sample known to be positive for Hepatitis B surface antigen (HBsAg) and Hepatitis B e antigen (HBeAg). The worker has completed the HBV vaccination series and has a documented anti-HBs titer >10 mIU/mL one month ago. What is the recommended post-exposure prophylaxis?
- A. Both HBIG and HBV vaccine booster dose
- B. Hepatitis B immune globulin (HBIG) only
- C. No treatment required
- D. Hepatitis B vaccine booster dose only
Answer: C
NEW QUESTION # 58
Which pattern on a Kirby-Bauer disk diffusion plate, showing resistance of Staphylococcus aureus to erythromycin but susceptibility to clindamycin with a flattening of the clindamycin zone adjacent to the erythromycin disk (D-zone test positive), indicates inducible clindamycin resistance?
- A. Indicates the strain possesses the msrA gene
- B. Indicates the strain should be reported as clindamycin susceptible
- C. Indicates the strain is tolerant to clindamycin
- D. Indicates the strain possesses an erm gene and should be reported as clindamycin resistant
Answer: D
NEW QUESTION # 59
A clinical microbiology laboratory is performing antimicrobial susceptibility testing using the broth microdilution method. The minimum bactericidal concentration (MBC) is determined by:
- A. Comparing the zone of inhibition around antibiotic disks to standardized tables.
- B. The lowest concentration of antibiotic that inhibits visible growth after 24 hours of incubation.
- C. Subculturing the clear wells from the MIC assay onto antibiotic-free media and determining the lowest concentration that results in no bacterial growth.
- D. The highest concentration of antibiotic that allows visible growth after 24 hours of incubation.
Answer: C
NEW QUESTION # 60
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