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American Society of Microbiology ABMM Sample Questions (Q33-Q38):NEW QUESTION # 33
A clinical microbiology laboratory is using PCR to detect the presence of the mecA gene in Staphylococcus aureus isolates. The mecA gene encodes for:
- A. Beta-lactamase enzyme
- B. An aminoglycoside-modifying enzyme
- C. Altered penicillin-binding protein (PBP2a)
- D. An efflux pump protein
Answer: C
NEW QUESTION # 34
Microscopic examination of a potassium hydroxide (KOH) preparation of skin scrapings from a patient with tinea versicolor typically reveals:
- A. Short, unbranched hyphae and globose yeast cells in clusters ("spaghetti and meatballs")
- B. Septate hyphae and arthroconidia
- C. Cigar-shaped yeast cells
- D. Broad, aseptate hyphae with sporangiophores
Answer: A
NEW QUESTION # 35
A clinical microbiology laboratory is performing quality control on antimicrobial susceptibility testing. The zone diameter for Escherichia coli ATCC 25922 tested against ciprofloxacin is consistently smaller than the acceptable range published by CLSI. The MOST likely cause of this discrepancy is:
- A. Incubation at an incorrect temperature
- B. Use of expired antibiotic disks
- C. Inoculation with a bacterial suspension that is too dense
- D. All of the above
Answer: D
NEW QUESTION # 36
A research team is investigating the mechanism of bacterial resistance to a novel fluoroquinolone antibiotic.
They isolate a resistant strain of Escherichia coli from a patient with a urinary tract infection. Genetic analysis of this strain reveals a point mutation in the gyrA gene. This mutation MOST likely results in:
- A. Production of an enzyme that inactivates the fluoroquinolone molecule.
- B. Alteration of the DNA gyrase enzyme, reducing its affinity for the fluoroquinolone.
- C. Increased expression of efflux pumps that actively transport the antibiotic out of the cell.
- D. Modification of the ribosomal target site, preventing antibiotic binding.
Answer: B
NEW QUESTION # 37
Microscopic examination of a trichrome-stained stool smear reveals amoebic trophozoites approximately 25
µm in diameter, containing ingested red blood cells. The nucleus, when visible, has fine, evenly distributed peripheral chromatin and a small, central karyosome. These features are diagnostic for:
- A. Iodamoeba bütschlii
- B. Entamoeba histolytica
- C. Endolimax nana
- D. Entamoeba coli
Answer: B
NEW QUESTION # 38
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